Effect of Auristatin PHE on Microtubule Integrity and Nuclear Localization in Cryptococcus neoformans

The mechanism of action of the fungicidal peptide auristatin PHE was investigated in Cryptococcus neoformans. Since auristatin PHE causes budding arrest in C. neoformans (T. Woyke, G. R. Pettit, G. Winkelmann, and R. K. Pettit, Antimicrob. Agents Chemother. 45:3580-3584, 2001), microtubule integrity...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Woyke, Tanja, Roberson, Robert W., Pettit, George R., Winkelmann, Günther, Pettit, Robin K.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Mechanisms of Action: Physiological Effects
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3802-3808.2002
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