Energy-Dependent Accumulation of Norfloxacin and Porin Expression in Clinical Isolates of Klebsiella pneumoniae and Relationship to Extended-Spectrum β-Lactamase Production

The relationships between porin deficiency, active efflux of fluoroquinolones, and extended-spectrum β-lactamase (ESBL) production were determined for 53 clinical isolates of Klebsiella pneumoniae. Thirty-two ESBL-positive strains (including 22 strains expressing porins and 10 strains lacking porins...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Martínez-Martínez, Luis, Pascual, Alvaro, Conejo, María del Carmen, García, Isabel, Joyanes, Providencia, Doménech-Sánchez, Antonio, Benedí, Vicente Javier
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Mechanisms of Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC132737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.12.3926-3932.2002
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