Energy-Dependent Accumulation of Norfloxacin and Porin Expression in Clinical Isolates of Klebsiella pneumoniae and Relationship to Extended-Spectrum β-Lactamase Production

The relationships between porin deficiency, active efflux of fluoroquinolones, and extended-spectrum β-lactamase (ESBL) production were determined for 53 clinical isolates of Klebsiella pneumoniae. Thirty-two ESBL-positive strains (including 22 strains expressing porins and 10 strains lacking porins...

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Main Authors: Martínez-Martínez, Luis, Pascual, Alvaro, Conejo, María del Carmen, García, Isabel, Joyanes, Providencia, Doménech-Sánchez, Antonio, Benedí, Vicente Javier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC132737/
https://ncbi.nlm.nih.gov/pubmed/12435697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.12.3926-3932.2002
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