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The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression

Menin is the product of the tumor suppressor gene Men1 that is mutated in the inherited tumor syndrome multiple endocrine neoplasia type 1 (MEN1). Menin has been shown to interact with SET-1 domain-containing histone 3 lysine 4 (H3K4) methyltransferases including mixed lineage leukemia proteins to r...

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Hlavní autoři: Chen, Ya-Xiong, Yan, Jizhou, Keeshan, Karen, Tubbs, Anthony T., Wang, Haoren, Silva, Albert, Brown, Eric J., Hess, Jay L., Pear, Warren S., Hua, Xianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326489/
https://ncbi.nlm.nih.gov/pubmed/16415155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510347103
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