Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains

The serine protease plasmin can efficiently degrade amyloid peptide in vitro, and is found at low levels in the hippocampus of patients with Alzheimer's disease (AD). The cause of such paucity remains unknown. We show here that the levels of total brain plasminogen and plasminogen-binding molec...

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Main Authors: Ledesma, Maria Dolores, Abad-Rodriguez, José, Galvan, Cristian, Biondi, Elisa, Navarro, Pilar, Delacourte, Andre, Dingwall, Colin, Dotti, Carlos G
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2003
Ábhair:
Scientific Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326416/
https://ncbi.nlm.nih.gov/pubmed/14618158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400021
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