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Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains
The serine protease plasmin can efficiently degrade amyloid peptide in vitro, and is found at low levels in the hippocampus of patients with Alzheimer's disease (AD). The cause of such paucity remains unknown. We show here that the levels of total brain plasminogen and plasminogen-binding molec...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326416/ https://ncbi.nlm.nih.gov/pubmed/14618158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400021 |
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