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The role of positively charged amino acids and electrostatic interactions in the complex of U1A protein and U1 hairpin II RNA
Previous kinetic investigations of the N-terminal RNA recognition motif (RRM) domain of spliceosomal protein U1A, interacting with its RNA target U1 hairpin II, provided experimental evidence for a ‘lure and lock’ model of binding in which electrostatic interactions first guide the RNA to the protei...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1326249/ https://ncbi.nlm.nih.gov/pubmed/16407334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj436 |
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