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Kinetic analysis of the role of the tyrosine 13, phenylalanine 56 and glutamine 54 network in the U1A/U1 hairpin II interaction

The A protein of the U1 small nuclear ribonucleoprotein particle, interacting with its stem–loop RNA target (U1hpII), is frequently used as a paradigm for RNA binding by recognition motif domains (RRMs). U1A/U1hpII complex formation has been proposed to consist of at least two steps: electrostatical...

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Autori principali: Law, Michael J., Chambers, Eric J., Katsamba, Phinikoula S., Haworth, Ian S., Laird-Offringa, Ite A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140079/
https://ncbi.nlm.nih.gov/pubmed/15914668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki602
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