PTEN negatively regulates neural stem cell self-renewal by modulating G(0)-G(1) cell cycle entry

Previous studies have demonstrated that a small subpopulation of brain tumor cells share key characteristics with neural stem/progenitor cells in terms of phenotype and behavior. These findings suggest that brain tumors might contain “cancer stem cells” that are critical for tumor growth. However, t...

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Detalhes bibliográficos
Main Authors: Groszer, Matthias, Erickson, Rebecca, Scripture-Adams, Deirdre D., Dougherty, Joseph D., Le Belle, Janel, Zack, Jerome A., Geschwind, Daniel H., Liu, Xin, Kornblum, Harley I., Wu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325011/
https://ncbi.nlm.nih.gov/pubmed/16373498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509939103
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