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Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

The majority of research on reactive oxygen species (ROS) has focused on their cellular toxicities. Stem cells generally have been thought to maintain low levels of ROS as a protection against these processes. However, recent studies suggest that ROS can also play roles as second messengers, activat...

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Detalhes bibliográficos
Main Authors: Le Belle, Janel E., Orozco, Nicolas M., Paucar, Andres A., Saxe, Jonathan P., Mottahedeh, Jack, Pyle, April D., Wu, Hong, Kornblum, Harley I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018289/
https://ncbi.nlm.nih.gov/pubmed/21211782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.11.028
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