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Ribosome exit tunnel can entropically stabilize α-helices
Several experiments have suggested that newly synthesized polypeptide chains can adopt helical structures deep within the ribosome exit tunnel. We hypothesize that confinement in the roughly cylindrical tunnel can entropically stabilize α-helices. The hypothesis is validated by using theory and simu...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1323178/ https://ncbi.nlm.nih.gov/pubmed/16357202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508234102 |
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