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The global transcriptional regulatory network for metabolism in Escherichia coli exhibits few dominant functional states

A principal aim of systems biology is to develop in silico models of whole cells or cellular processes that explain and predict observable cellular phenotypes. Here, we use a model of a genome-scale reconstruction of the integrated metabolic and transcriptional regulatory networks for Escherichia co...

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Autori principali: Barrett, Christian L., Herring, Christopher D., Reed, Jennifer L., Palsson, Bernhard O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323155/
https://ncbi.nlm.nih.gov/pubmed/16357206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505231102
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