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Global transcriptional regulatory network for Escherichia coli robustly connects gene expression to transcription factor activities

Transcriptional regulatory networks (TRNs) have been studied intensely for >25 y. Yet, even for the Escherichia coli TRN—probably the best characterized TRN—several questions remain. Here, we address three questions: (i) How complete is our knowledge of the E. coli TRN; (ii) how well can we predi...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Fang, Xin, Sastry, Anand, Mih, Nathan, Kim, Donghyuk, Tan, Justin, Yurkovich, James T., Lloyd, Colton J., Gao, Ye, Yang, Laurence, Palsson, Bernhard O.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617254/
https://ncbi.nlm.nih.gov/pubmed/28874552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702581114
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