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Posttranslational conversion of l-serines to d-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147

As a general rule, ribosomally synthesized polypeptides contain amino acids only in the l-isoform in an order dictated by the coding DNA/RNA. Two of a total of only four examples of l to d conversions in prokaryotic systems occur in posttranslationally modified antimicrobial peptides called lantibio...

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Detalhes bibliográficos
Main Authors: Cotter, Paul D., O'Connor, Paula M., Draper, Lorraine A., Lawton, Elaine M., Deegan, Lucy H., Hill, Colin, Ross, R. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317978/
https://ncbi.nlm.nih.gov/pubmed/16339304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509371102
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