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Homologues and Bioengineered Derivatives of LtnJ Vary in Ability to Form d-Alanine in the Lantibiotic Lacticin 3147
Ltnα and Ltnβ are individual components of the two-peptide lantibiotic lacticin 3147 and are unusual in that, although ribosomally synthesized, they contain d-amino acids. These result from the dehydration of l-serine to dehydroalanine by LtnM and subsequent stereospecific hydrogenation to d-alanine...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264081/ https://ncbi.nlm.nih.gov/pubmed/22123251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06185-11 |
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