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Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser(428)

PDE3A (phosphodiesterase 3A) was identified as a phosphoprotein that co-immunoprecipitates with endogenous 14-3-3 proteins from HeLa cell extracts, and binds directly to 14-3-3 proteins in a phosphorylation-dependent manner. Among cellular stimuli tested, PMA promoted maximal binding of PDE3A to 14-...

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Bibliografiske detaljer
Main Authors: Pozuelo Rubio, Mercedes, Campbell, David G., Morrice, Nicholas A., Mackintosh, Carol
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317675/
https://ncbi.nlm.nih.gov/pubmed/16153182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051103
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