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“UnPAKing” Human Immunodeficiency Virus (HIV) Replication: Using Small Interfering RNA Screening To Identify Novel Cofactors and Elucidate the Role of Group I PAKs in HIV Infection

In order to identify novel proviral host factors involved in human immunodeficiency virus (HIV) infection, we performed a screen of a small interfering RNA (siRNA) library targeting 5,000 genes with the highest potential for being targets for therapeutics. Many siRNAs in the library against known ho...

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Detalhes bibliográficos
Main Authors: Nguyen, Deborah G., Wolff, Karen C., Yin, Hong, Caldwell, Jeremy S., Kuhen, Kelli L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317519/
https://ncbi.nlm.nih.gov/pubmed/16352537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.130-137.2006
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