Elucidating and Minimizing the Loss by Recombinant Vaccinia Virus of Human Immunodeficiency Virus Gene Expression Resulting from Spontaneous Mutations and Positive Selection

While characterizing modified vaccinia virus recombinants (rMVAs) containing human immunodeficiency virus env and gag-pol genes, we detected nonexpressing mutants by immunostaining individual plaques. In many cases, the numbers of mutants increased during successive passages, indicating strong selec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wyatt, Linda S., Earl, Patricia L., Xiao, Wei, Americo, Jeffrey L., Cotter, Catherine A., Vogt, Jennifer, Moss, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704791/
https://ncbi.nlm.nih.gov/pubmed/19420086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00687-09
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados