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Interaction of Moloney Murine Leukemia Virus Capsid with Ubc9 and PIASy Mediates SUMO-1 Addition Required Early in Infection

Yeast two-hybrid screens led to the identification of Ubc9 and PIASy, the E2 and E3 small ubiquitin-like modifier (SUMO)-conjugating enzymes, as proteins interacting with the capsid (CA) protein of the Moloney murine leukemia virus. The binding site in CA for Ubc9 was mapped by deletion and alanine-...

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Detalhes bibliográficos
Main Authors: Yueh, Andrew, Leung, Juliana, Bhattacharyya, Subarna, Perrone, Lucy A., de los Santos, Kenia, Pu, Szy-yuan, Goff, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317516/
https://ncbi.nlm.nih.gov/pubmed/16352559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.342-352.2006
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