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Recombinant prion protein does not possess SOD-1 activity

A considerable body of evidence now shows that PrP (prion protein) binds metal ions with high affinity and it has been claimed that the binding of copper (II) ions to PrP confers SOD (superoxide dismutase) activity. In turn, it has been suggested that PrP is a synaptic dismutase and that loss of thi...

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מידע ביבליוגרפי
Main Authors: Jones, Samantha, Batchelor, Mark, Bhelt, Daljit, Clarke, Anthony R., Collinge, John, Jackson, Graham S.
פורמט: Artigo
שפה:Inglês
יצא לאור: Portland Press Ltd. 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316266/
https://ncbi.nlm.nih.gov/pubmed/16156720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051236
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