Location and properties of metal-binding sites on the human prion protein
Although a functional role in copper binding has been suggested for the prion protein, evidence for binding at affinities characteristic of authentic metal-binding proteins has been lacking. By presentation of copper(II) ions in the presence of the weak chelator glycine, we have now characterized tw...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151038498 |
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