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Developing a programmed restriction endonuclease for highly specific DNA cleavage
Specific cleavage of large DNA molecules at few sites, necessary for the analysis of genomic DNA or for targeting individual genes in complex genomes, requires endonucleases of extremely high specificity. Restriction endonucleases (REase) that recognize DNA sequences of 4–8 bp are not sufficiently s...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316111/ https://ncbi.nlm.nih.gov/pubmed/16356926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki1009 |
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