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Developing a programmed restriction endonuclease for highly specific DNA cleavage
Specific cleavage of large DNA molecules at few sites, necessary for the analysis of genomic DNA or for targeting individual genes in complex genomes, requires endonucleases of extremely high specificity. Restriction endonucleases (REase) that recognize DNA sequences of 4–8 bp are not sufficiently s...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316111/ https://ncbi.nlm.nih.gov/pubmed/16356926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki1009 |
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