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Developing a programmed restriction endonuclease for highly specific DNA cleavage

Specific cleavage of large DNA molecules at few sites, necessary for the analysis of genomic DNA or for targeting individual genes in complex genomes, requires endonucleases of extremely high specificity. Restriction endonucleases (REase) that recognize DNA sequences of 4–8 bp are not sufficiently s...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Eisenschmidt, Kristin, Lanio, Thomas, Simoncsits, András, Jeltsch, Albert, Pingoud, Vera, Wende, Wolfgang, Pingoud, Alfred
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316111/
https://ncbi.nlm.nih.gov/pubmed/16356926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki1009
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