Interaction of Ritonavir-Boosted Tipranavir with Loperamide Does Not Result in Loperamide-Associated Neurologic Side Effects in Healthy Volunteers

Loperamide (LOP) is a peripherally acting opioid receptor agonist used for the management of chronic diarrhea through the reduction of gut motility. The lack of central opioid effects is partly due to the efflux activity of the multidrug resistance transporter P-glycoprotein (P-gp) at the blood-brai...

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Detalhes bibliográficos
Main Authors: Mukwaya, Geoffrey, MacGregor, Thomas, Hoelscher, David, Heming, Thomas, Legg, Daniel, Kavanaugh, Kelli, Johnson, Phillip, Sabo, John P., McCallister, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315935/
https://ncbi.nlm.nih.gov/pubmed/16304151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.4903-4910.2005
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