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Steady-State Disposition of the Nonpeptidic Protease Inhibitor Tipranavir when Coadministered with Ritonavir

The pharmacokinetic and metabolite profiles of the antiretroviral agent tipranavir (TPV), administered with ritonavir (RTV), in nine healthy male volunteers were characterized. Subjects received 500-mg TPV capsules with 200-mg RTV capsules twice daily for 6 days. They then received a single oral dos...

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Bibliografiset tiedot
Päätekijät: Chen, Linzhi, Sabo, John P., Philip, Elsy, Mao, Yanping, Norris, Stephen H., MacGregor, Thomas R., Wruck, Jan M., Garfinkel, Sandra, Castles, Mark, Brinkman, Amy, Valdez, Hernan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913264/
https://ncbi.nlm.nih.gov/pubmed/17485497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01115-06
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