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Steady-State Disposition of the Nonpeptidic Protease Inhibitor Tipranavir when Coadministered with Ritonavir

The pharmacokinetic and metabolite profiles of the antiretroviral agent tipranavir (TPV), administered with ritonavir (RTV), in nine healthy male volunteers were characterized. Subjects received 500-mg TPV capsules with 200-mg RTV capsules twice daily for 6 days. They then received a single oral dos...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chen, Linzhi, Sabo, John P., Philip, Elsy, Mao, Yanping, Norris, Stephen H., MacGregor, Thomas R., Wruck, Jan M., Garfinkel, Sandra, Castles, Mark, Brinkman, Amy, Valdez, Hernan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913264/
https://ncbi.nlm.nih.gov/pubmed/17485497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01115-06
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