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Steady-State Disposition of the Nonpeptidic Protease Inhibitor Tipranavir when Coadministered with Ritonavir

The pharmacokinetic and metabolite profiles of the antiretroviral agent tipranavir (TPV), administered with ritonavir (RTV), in nine healthy male volunteers were characterized. Subjects received 500-mg TPV capsules with 200-mg RTV capsules twice daily for 6 days. They then received a single oral dos...

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Detalhes bibliográficos
Main Authors: Chen, Linzhi, Sabo, John P., Philip, Elsy, Mao, Yanping, Norris, Stephen H., MacGregor, Thomas R., Wruck, Jan M., Garfinkel, Sandra, Castles, Mark, Brinkman, Amy, Valdez, Hernan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913264/
https://ncbi.nlm.nih.gov/pubmed/17485497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01115-06
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