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Pharmacodynamics of Caspofungin in a Murine Model of Systemic Candidiasis: Importance of Persistence of Caspofungin in Tissues to Understanding Drug Activity

Pharmacokinetic and pharmacodynamic studies were conducted in a murine model of systemic candidiasis to determine the pharmacodynamic parameter linked with caspofungin efficacy. Additional studies defined the importance of persistent tissue drug concentrations to treatment outcome. The pharmacokinet...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Louie, Arnold, Deziel, Mark, Liu, Weiguo, Drusano, Michael F., Gumbo, Tawanda, Drusano, George L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315924/
https://ncbi.nlm.nih.gov/pubmed/16304173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.5058-5068.2005
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