Activities of Acyclic Nucleoside Phosphonates against Orf Virus in Human and Ovine Cell Monolayers and Organotypic Ovine Raft Cultures

Orf virus, a member of the Parapoxvirus genus, causes a contagious pustular dermatitis in sheep, goats, and humans. Previous studies have demonstrated the activity of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC; cidofovir; Vistide) against orf virus in cell culture and humans. We hav...

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Detalhes bibliográficos
Main Authors: Dal Pozzo, F., Andrei, G., Holý, A., Van Den Oord, J., Scagliarini, A., De Clercq, E., Snoeck, R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315923/
https://ncbi.nlm.nih.gov/pubmed/16304144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.4843-4852.2005
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