Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates

A novel class of acyclic nucleoside phosphonates has been discovered in which the base consists of a pyrimidine preferably containing an amino group at C-2 and C-4 and a 2-(phosphonomethoxy)ethoxy (PMEO) or a 2-(phosphonomethoxy)propoxy (PMPO) group at C-6. The 6-PMEO 2,4-diaminopyrimidine (compound...

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Detalhes bibliográficos
Main Authors: Balzarini, J., Pannecouque, C., De Clercq, E., Aquaro, S., Perno, C.-F., Egberink, H., Holý, A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127315/
https://ncbi.nlm.nih.gov/pubmed/12069973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2185-2193.2002
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