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Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates

A novel class of acyclic nucleoside phosphonates has been discovered in which the base consists of a pyrimidine preferably containing an amino group at C-2 and C-4 and a 2-(phosphonomethoxy)ethoxy (PMEO) or a 2-(phosphonomethoxy)propoxy (PMPO) group at C-6. The 6-PMEO 2,4-diaminopyrimidine (compound...

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Sparad:
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Balzarini, J., Pannecouque, C., De Clercq, E., Aquaro, S., Perno, C.-F., Egberink, H., Holý, A.
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 2002
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127315/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2185-2193.2002
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