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A rotary pumping model for helicase function of MCM proteins at a distance from replication forks
We propose an integrated model for eukaryotic DNA replication to explain the following problems: (1) How is DNA spooled through fixed sites of replication? (2) What and where are the helicases that unwind replicating DNA? (3) Why are the best candidates for replicative helicases, namely mini-chromos...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315806/ https://ncbi.nlm.nih.gov/pubmed/12524516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor706 |
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