MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression primarily through translational repression. In erythropoietic (E) culture of cord blood CD34+ progenitor cells, the level of miR 221 and 222 is gradually and sharply down-modulated. Hypothetically, this decline could promote ery...

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Autori principali: Felli, Nadia, Fontana, Laura, Pelosi, Elvira, Botta, Rosanna, Bonci, Desirée, Facchiano, Francesco, Liuzzi, Francesca, Lulli, Valentina, Morsilli, Ornella, Santoro, Simona, Valtieri, Mauro, Calin, George Adrian, Liu, Chang-Gong, Sorrentino, Antonio, Croce, Carlo M., Peschle, Cesare
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1312381/
https://ncbi.nlm.nih.gov/pubmed/16330772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506216102
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