The Inhibition of the Highly Expressed Mir-221 and Mir-222 Impairs the Growth of Prostate Carcinoma Xenografts in Mice

BACKGROUND: MiR-221 and miR-222 are two highly homologous microRNAs whose upregulation has been recently described in several types of human tumors, for some of which their oncogenic role was explained by the discovery of their target p27, a key cell cycle regulator. We previously showed this regula...

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Autori principali: Mercatelli, Neri, Coppola, Valeria, Bonci, Desirée, Miele, Francesca, Costantini, Arianna, Guadagnoli, Marco, Bonanno, Elena, Muto, Giovanni, Frajese, Giovanni Vanni, De Maria, Ruggero, Spagnoli, Luigi Giusto, Farace, Maria Giulia, Ciafrè, Silvia Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603596/
https://ncbi.nlm.nih.gov/pubmed/19107213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004029
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