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The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing

The low-density lipoprotein receptor-related protein (LRP) has recently been implicated in numerous intracellular signaling functions, as well as in Alzheimer’s disease pathogenesis. Studies have shown that the β-amyloid precursor protein (APP) interacts with LRP and that this association may impact...

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Detalhes bibliográficos
Main Authors: Pietrzik, Claus U., Busse, Tracy, Merriam, David E., Weggen, Sascha, Koo, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC131065/
https://ncbi.nlm.nih.gov/pubmed/12411487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf568
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