FE65 Constitutes the Functional Link between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein

Increasing evidence has implicated the low density lipoprotein receptor-related protein (LRP) and the adaptor protein FE65 in Alzheimer's disease pathogenesis. We have shown previously that LRP mediates β-amyloid precursor protein (APP) processing and affects amyloid β-protein and APP secretion...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Pietrzik, Claus U., Yoon, Il-Sang, Jaeger, Sebastian, Busse, Tracy, Weggen, Sascha, Koo, Edward H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Neurobiology of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729272/
https://ncbi.nlm.nih.gov/pubmed/15115822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5451-03.2004
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