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Reversible stages of the low-pH-triggered conformational change in influenza virus hemagglutinin
The refolding of the prototypic fusogenic protein hemagglutinin (HA) at the pH of fusion is considered to be a concerted and irreversible discharge of a loaded spring, with no distinct intermediates between the initial and final conformations. Here, we show that HA refolding involves reversible conf...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC131056/ https://ncbi.nlm.nih.gov/pubmed/12411488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf559 |
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