Detection of Ethambutol-Resistant Mycobacterium tuberculosis Strains by Multiplex Allele-Specific PCR Assay Targeting embB306 Mutations

We describe a multiplex allele-specific (MAS)-PCR assay to detect simultaneously mutations in the first and third bases of the embB gene codon 306ATG. These mutations are known to confer ethambutol (EMB) resistance in the majority of clinical Mycobacterium tuberculosis isolates worldwide. The mutate...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Clin Microbiol
Prif Awduron:	Mokrousov, Igor, Narvskaya, Olga, Limeschenko, Elena, Otten, Tatiana, Vyshnevskiy, Boris
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2002
Pynciau:	Mycobacteriology and Aerobic Actinomycetes
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11980930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.40.5.1617-1620.2002
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!