Detection of Ethambutol-Resistant Mycobacterium tuberculosis Strains by Multiplex Allele-Specific PCR Assay Targeting embB306 Mutations

We describe a multiplex allele-specific (MAS)-PCR assay to detect simultaneously mutations in the first and third bases of the embB gene codon 306ATG. These mutations are known to confer ethambutol (EMB) resistance in the majority of clinical Mycobacterium tuberculosis isolates worldwide. The mutate...

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izdano v:	J Clin Microbiol
Principais autores:	Mokrousov, Igor, Narvskaya, Olga, Limeschenko, Elena, Otten, Tatiana, Vyshnevskiy, Boris
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Mycobacteriology and Aerobic Actinomycetes
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11980930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.40.5.1617-1620.2002
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