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Precise and Parallel Characterization of Coding Polymorphisms, Alternative Splicing and Modifications in Human Proteins by Mass Spectrometry
The human proteome is a highly complex extension of the genome wherein a single gene often produces distinct protein forms due to alternative splicing, RNA-editing, polymorphisms, and posttranslational modifications (PTMs). Such biological variation compounded by the high sequence identity within ge...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1307493/ https://ncbi.nlm.nih.gov/pubmed/15863400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M500064-MCP200 |
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