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“Proteotyping”: Population Proteomics of Human Leukocytes Using Top Down Mass Spectrometry
Characterizing combinations of coding polymorphisms (cSNPs), alternative splicing and post-translational modifications (PTMs) on a single protein by standard peptide-based proteomics is challenging owing to <100% sequence coverage and the uncoupling effect of proteolysis on such variations >10...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615201/ https://ncbi.nlm.nih.gov/pubmed/18351787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac800141g |
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