Tandem Mass Spectrometry with Ultrahigh Mass Accuracy Clarifies Peptide Identification by Database Retrieval

A platform was developed to analyze MS/MS spectra from large peptides with low part-per-million mass accuracy, including a commercial-grade software suite. Termed Middle Down Proteomics, this platform identified 7454 peptides from 2–20 kDa (1472 unique) from 555 proteins after 23 LC-MS/MS injections...

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Bibliographische Detailangaben
Hauptverfasser: Boyne, Michael T., Garcia, Benjamin A., Li, Mingxi, Zamdborg, Leonid, Wenger, Craig D., Babai, Shannee, Kelleher, Neil L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753674/
https://ncbi.nlm.nih.gov/pubmed/19053528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr800635m
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