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On the Scalability and Requirements of Whole Protein Mass Spectrometry

Top-down proteomics has improved over the last decade despite the significant challenges presented by the analysis of large protein ions. Here, the detection of these high mass species by electrospray-based mass spectrometry (MS) is examined from a theoretical perspective to understand the mass-depe...

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Detalhes bibliográficos
Main Authors: Compton, Philip D., Zamdborg, Leonid, Thomas, Paul M., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165072/
https://ncbi.nlm.nih.gov/pubmed/21744800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac2010795
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