Community-Based Safety, Immunogenicity, and Transmissibility Study of the Shigella sonnei WRSS1 Vaccine in Israeli Volunteers

We describe the first community-based evaluation of Shigella sonnei strain WRSS1, a live, oral candidate vaccine attenuated by a 212-bp deletion in the virG (or icsA) plasmid virulence gene. Three single-dose regimens of WRSS1 (5 × 10(3) CFU, 2 × 10(4) CFU, and 4 × 10(5) CFU) were tested with cohort...

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Detaylı Bibliyografya
Asıl Yazarlar: Orr, Nadav, Katz, David E., Atsmon, Jacob, Radu, Paull, Yavzori, Miri, Halperin, Tamar, Sela, Tamar, Kayouf, Raid, Klein, Zivit, Ambar, Ruhama, Cohen, Dani, Wolf, Marcia K., Venkatesan, Malabi M., Hale, Thomas L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307051/
https://ncbi.nlm.nih.gov/pubmed/16299296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8027-8032.2005
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