Pyrimethamine and WR99210 exert opposing selection on dihydrofolate reductase from Plasmodium vivax
Plasmodium vivax is a major public health problem in Asia and South and Central America where it is most prevalent. Until very recently, the parasite has been effectively treated with chloroquine, but resistance to this drug has now been reported in several areas. Affordable alternative treatments f...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.182295999 |
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