Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

Genomic DNA copy number alterations are key genetic events in the development and progression of human cancers. Here we report a genome-wide microarray comparative genomic hybridization (array CGH) analysis of DNA copy number variation in a series of primary human breast tumors. We have profiled DNA...

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Hauptverfasser: Pollack, Jonathan R., Sørlie, Therese, Perou, Charles M., Rees, Christian A., Jeffrey, Stefanie S., Lonning, Per E., Tibshirani, Robert, Botstein, David, Børresen-Dale, Anne-Lise, Brown, Patrick O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC130569/
https://ncbi.nlm.nih.gov/pubmed/12297621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162471999
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