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Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer

<p>Abstract</p> <p>Background</p> <p>Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biological pathways of regulation. Most current approaches either depend on linear correlation or on no...

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Bibliografske podrobnosti
Principais autores: Frigessi Arnoldo, Lingjærde Ole, Solvang Hiroko K, Børresen-Dale Anne-Lise, Kristensen Vessela N
Format: Artigo
Jezik:Inglês
Izdano: BMC 2011-05-01
Serija:BMC Bioinformatics
Online dostop:http://www.biomedcentral.com/1471-2105/12/197
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