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Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data.

Genomic copy number alterations are common in cancer. Finding the genes causally implicated in oncogenesis is challenging because the gain or loss of a chromosomal region may affect a few key driver genes and many passengers. Integrative analyses have opened new vistas for addressing this issue. One...

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Hlavní autoři: Miriam Ragle Aure, Israel Steinfeld, Lars Oliver Baumbusch, Knut Liestøl, Doron Lipson, Sandra Nyberg, Bjørn Naume, Kristine Kleivi Sahlberg, Vessela N Kristensen, Anne-Lise Børresen-Dale, Ole Christian Lingjærde, Zohar Yakhini
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3559658?pdf=render
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