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Maximum Likelihood Estimation of Ion Channel Kinetics from Macroscopic Currents
We describe a maximum likelihood method for direct estimation of rate constants from macroscopic ion channel data for kinetic models of arbitrary size and topology. The number of channels in the preparation, and the mean and standard deviation of the unitary current can be estimated, and a priori co...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1305347/ https://ncbi.nlm.nih.gov/pubmed/15681642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.053256 |
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