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Estimation of Ion Channel Kinetics from Fluctuations of Macroscopic Currents
For single channel recordings, the maximum likelihood estimation (MLE) of kinetic rates and conductance is well established. A direct extrapolation of this method to macroscopic currents is computationally prohibitive: it scales as a power of the number of channels. An approximated MLE that ignored...
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| Formato: | Artigo |
| Idioma: | Inglês |
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The Biophysical Society
2007
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914441/ https://ncbi.nlm.nih.gov/pubmed/17416622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.101212 |
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