Functional Interaction of Ca(V) Channel Isoforms with Ryanodine Receptors Studied in Dysgenic Myotubes

The L-type Ca(2+) channels Ca(V)1.1 (α(1S)) and Ca(V)1.2 (α(1C)) share properties of targeting but differ by their mode of coupling to ryanodine receptors in muscle cells. The brain isoform Ca(V)2.1 (α(1A)) lacks ryanodine receptor targeting. We studied these three isoforms in myotubes of the α(1S)-...

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Bibliographische Detailangaben
Hauptverfasser: Schuhmeier, Ralph Peter, Gouadon, Elodie, Ursu, Daniel, Kasielke, Nicole, Flucher, Bernhard E., Grabner, Manfred, Melzer, Werner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2005
Schlagworte:
Channels, Receptors, and Electrical Signaling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305232/
https://ncbi.nlm.nih.gov/pubmed/15626717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051318
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